Outcomes associated with receiving an early versus late diagnosis of
 
   Lead Investigator:    Amie Shei
   Institution      :    Analysis Group, Inc.
   E-Mail           :    amie.shei@analysisgroup.com
   Proposal ID      :    597


   Publications:


1  Kirson NY, Andrews JS, Shei A, King S, Schonfeld S, Birnbaum HG, Ball D, Kahle-Wrobleski K
   Patient Characteristics and Outcomes Associated with Receiving an Earlier Versus Later Diagnosis of Probable Alzheimer's Disease: Evidence from the National Alzheimer's Coordinating Center Data
   Abstract  Alzheimers Dement,12:P698,2016,

   PUBLISHED





   Proposal Description:
   To the best of our knowledge, no study to date has evaluated the impact of        receiving delayed Alzheimer???s disease diagnosis on the clinical and             functional attributes of the patients. The aim of this project is to further      the understanding of the characteristics of patients receiving early versus       late Alzheimer???s disease diagnosis and of the outcomes associated with          receiving an Alzheimer???s disease diagnosis at various time points in relation   to the onset of cognitive decline. Having a better understanding of these         outcomes is particularly relevant given recent developments in diagnostic         technologies that may facilitate earlier identification of Alzheimer???s          disease-type pathologies and the potential for future therapeutic developments.                                                                                     In order to better understand outcomes associated with receiving an               Alzheimer???s disease diagnosis at various time points in relation to the onset   of cognitive decline, the project will have the following primary objectives:     1. Evaluate the time between onset of cognitive decline and first Alzheimer???s   disease diagnosis                                                                 2. Compare the demographic and clinical characteristics of patients receiving     an early Alzheimer???s disease diagnosis to those that receive a late             Alzheimer???s disease diagnosis                                                   3. Identify predictors of receiving an early Alzheimer???s disease diagnosis      versus receiving a late Alzheimer???s disease diagnosis                           4. Compare the outcomes associated with receiving an early Alzheimer???s          disease diagnosis versus receiving a late Alzheimer???s disease diagnosis